Inactivation of recombinant bacteriophage lambda by use of chemical agents and UV radiation.

نویسندگان

  • Ewan M Clark
  • Harry Wright
  • Kelly-Anne Lennon
  • Vicki A Craik
  • Jason R Clark
  • John B March
چکیده

Several approaches for the inactivation of bacteriophage lambda, including UV germicidal irradiation (UVGI) and the chemical agents Virkon-S, Chloros, Decon-90, and sodium hydroxide (NaOH), were compared. Virkon, NaOH, and UVGI caused a ≥7-log(10) reduction in phage titers. This study successfully describes several methods with potential for bacteriophage inactivation in industrial settings.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 78 8  شماره 

صفحات  -

تاریخ انتشار 2012